| Many scientific advances start with
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| | absent in normal cells...This makes an
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| serendipity. Scientists at Wake Forest
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| | exciting treatment target because
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| University have made a surprising
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| | theoretically you don't have to worry
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| discovery - an obesity drug can kill
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| | about harming nearby healthy tissue."
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| cancer cells. The researchers are now
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| | While oralist has killed cancer cells in
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| using the findings to develop more
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| | the lab, it can't be used as a cancer
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| effective cancer drugs.
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| | treatment, because in humans, it is
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| This study, published in the online
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| | designed to act only in the digestive
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| version of Nature Structural and
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| | tract. According to W. Todd Lowther,
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| Molecular Biology is the first to report
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| | Ph.D., another researcher on the project
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| that the drug oralist,XenicalÂ(R) or
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| | , the goal is to "develop an
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| AlliÂ(R) interacts and binds with a
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| | orlistat-like drug that can get into the
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| protein found in tumor cells causing cell
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| | bloodstream and go to the site of a
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| death. The project started when Steven
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| | tumor."
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| Kridel, Ph.D., an assistant professor in
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| | They are working with a dozen
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| the Department of Cancer Biology,
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| | possibilities to find the one that works
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| analyzed prostate cancer cells to see
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| | best. The drug will be tested on animals,
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| which enzymes were expressed at high
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| | and later cancer patients.
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| levels in the hope of developing
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| | While what they are working on is a
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| treatments that would inhibit those
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| | cancer treatment, as fatty acid synthase
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| enzymes and stop tumor growth.
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| | is also found in fat cells, it's possible
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| What they found according to Kridel is
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| | that, "You might have the same drug for
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| that, "a protein known as fatty acid
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| | treating a cancer patient as an obese
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| synthase is expressed at high levels in
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| | patient," said Lowther.
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| prostate tumor cells, and is fairly
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