Prostate Seed Implants: A Promising Treatment For Prostate Cancer

Prostate brachytherapy (pronouncedis taken to the operating room for the procedure,
bray-kee-ther-uh-pee), the implantation of radioactivewhere he undergoes either general or spinal
seeds into the prostate gland, is one of the standardanesthesia. Then, the radiation oncologist and the
methods of successfully treating prostate cancer.urologist work as a team to implant the seeds into
The tiny radioactive seeds are smaller than grains ofthe prostate, using transrectal ultrasound to guide the
rice.placement.
A prostate seed implant may be the only type ofThe Implant Process
radiation therapy needed by a man with low-riskUsing the treatment plan and fluoroscopy (real-time
prostate cancer or it may be prescribed in addition tox-ray), the radiation oncologist places the seeds
external beam radiation therapy in men withwithin the prostate. The entire procedure usually
intermediate- and high- risk prostate cancer. The goaltakes less than one hour. After the seed placement,
is to eradicate cancer cells while preserving healthy,the urologist performs a cystoscopy (a procedure in
surrounding tissue, such as the bladder, the urethrawhich a slender, flexible, fiber optic scope is inserted
(the tube that connects the bladder to the penis),from the penis into the bladder), to look for and
and the rectum.remove any seeds that dislodged in the bladder or
The advantages of prostate seed implants arethe urethra. Within the few next days, a CT scan is
significant. Fist, the procedure requires only minorobtained to verify the placement of the seeds.
surgery, usually causing fewer side effects thanProstate Seed Implants: Recovery
other treatments. Also, it is generally a same day,Because prostate implants do not involve major
outpatient procedure. Men usually are able to returnsurgery, side effects are rarely severe. The most
to work within several days, as long as they feel wellcommon side effects reported by men after
enough. In addition, recent reports suggest that theprostate seed implants are:
procedure, when performed on properly selected- Urinary frequency (60-70%)
men, is at least as effective as surgery to cure- Urinary burning (50%)
prostate cancer. Radiation exposure to other people- Urinary urgency (50%)
is minimal, so restrictions do not apply unless the man- Erectile dysfunction (30%)
is returning to a setting where a young child or- Blood in the urine (20-30%)
pregnant woman is present.- Increased bowel movements and bowel urgency
Treatment Planning(5%)
Men undergo a pre-implant ultrasound study to- Fatigue (20%)
determine where the radioactive seeds (and the- Pelvic pain (20%)
needles to implant them) should be placed. A- The need for temporary catheter placement
transrectal ultrasound, wherein an ultrasound probe is(10-15%)
carefully positioned in the rectum to view the entire- Urinary incontinence (less than 1%)
prostate, is performed. Images of the prostate areIn addition, up to 20 percent of men are found to
taken and are transferred to a special treatmenthave seed migration into their lungs. However, no
planning computer, which evaluates the position ofdetrimental effects have been reported. Infrequently,
the prostate and generates a three-dimensional planmen have required trans-urethral resection, the
that dictates the precise placement of the seeds."scraping" of the prostate gland via the penis, to
Preparation for the Procedurerelieve urinary obstruction after the seed placement.
Most candidates for prostate brachytherapy undergoFollow-Up
blood tests, a chest x-ray and an EKG several daysMen who undergo prostate brachytherapy report for
prior to the implant, in order to be approved forfollow-up visits four weeks after the procedure and
anesthesia. On the morning of the procedure, menevery three months thereafter. A PSA blood test
receive an enema to help optimize the quality of theand a physical exam are performed to assess the
transrectal ultrasound images. In addition, bloodstatus of the prostate.
thinners are discontinued several days prior to theThe good news is that prostate seed implants are
procedure to help diminish the risk of bleeding.usually successful at controlling prostate cancer within
Day of the Procedurethe gland. Such local control of disease correlates with
Typically, men who are scheduled to undergo seedrendering men free from prostate cancer.
placement arrive early in the morning. Next, the man