| Since its discovery in the late 1950's
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| | continued improvement in heart function
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| Coenzyme Q10 (CoQ10) has received much
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| | as well as steady and continued reduction
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| attention as a necessary compound for
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| | in patient symptoms including fatigue,
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| proper cellular function. It is the
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| | chest pains, palpitations and breathing
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| essential coenzyme necessary for the
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| | difficulty. Patients with more establish
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| production of ATP (adenosine
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| | and long-term cases showed gradual
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| triphosphate) upon which all cellular
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| | improvement but did not gain normal heart
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| functions depend. Without ATP our bodies
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| | function. Patients with newer cases of
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| cannot function properly. Without CoQ10,
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| | heart failure demonstrated much more
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| ATP cannot function. This connection has
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| | rapid improvement often returning to
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| made CoQ10 a very important object of
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| | normal heart function.Papers numbering in
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| study in relation to chronic disease.In
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| | the hundreds from eight different
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| many cases the presence of chronic
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| | symposia have been written and presented
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| disease is associated with inadequate
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| | on the effects of CoQ10 on heart disease.
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| levels of CoQ10. But no area of study has
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| | International clinical studies have also
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| received more attention than the relation
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| | been conducted in the United States,
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| between CoQ10 and heart disease. That is
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| | Japan, Germany, Italy and Sweden.
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| because CoQ10 is believed to be of
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| | Together these studies and the papers
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| fundamental importance in cells with high
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| | that have been derived from them
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| metabolic demands such as cardiac cells.
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| | demonstrate significant improvement in
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| A further reason the connection of heart
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| | heart muscle function while causing no
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| disease and CoQ10 has gained so much
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| | adverse effects.One particular area of
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| attention is because heart conditions of
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| | study involves diastolic dysfunction
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| many kinds are associated with
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| | which is one of the earliest signs of
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| chronically low CoQ10 levels.CoQ10 is
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| | myocardial failure. Diastole is the phase
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| highly concentrated in heart muscle cells
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| | of the cardiac cycle when the heart is
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| because of their high energy
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| | filled with returning blood. Because this
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| requirements. Add this to the fact that
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| | phase requires more cellular energy than
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| heart disease is the number one killer in
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| | the systolic phase (when the blood is
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| developed and developing countries and
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| | pushed out of the heart) it is more
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| one can see why the bulk of scientific
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| | dependent on CoQ10. Diastolic dysfunction
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| research on CoQ10 has been concerned with
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| | is a stiffening of the heart muscle which
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| heart disease. Specifically, studies on
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| | naturally restricts the heart's ability
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| congestive heart failure have
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| | to pump. This condition is associated
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| demonstrated a strong correlation between
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| | with many cardiac disorders. Hypertension
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| the severity of heart failure and the
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| | is among these disorders. As the heart
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| degree of CoQ10 deficiency. The lower the
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| | muscles become stiff there is often a
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| levels of CoQ10 in the heart muscles the
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| | corresponding rise in blood pressure.
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| more severe the heart failure. If indeed
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| | When the diastolic dysfunction is
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| CoQ10 deficiency is a primary cause of
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| | reversed, blood pressure tends to lower
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| congestive heart failure then, in such
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| | as well.In one study involving 109
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| cases, the remedy is simple and cost
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| | patients with hypertension, CoQ10
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| effective; CoQ10
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| | supplementation was added to normal
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| supplementation.Congestive heart failure
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| | hypertension treatments. In an average of
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| is a condition where the heart does not
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| | 4.4 months 51% of the patients were able
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| pump effectively resulting in an
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| | stop using at least one blood pressure
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| accumulation of fluid in the lungs.
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| | lowering medication. Some were able to
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| Symptoms may include shortness of breath,
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| | stop using up to three medications.
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| difficulty breathing when lying flat and
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| | Another study produced similar results.
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| leg or ankle swelling. Causes include
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| | In that study 43% of 424 patients were
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| chronic hypertension, cardiomyopathy
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| | able to stop using between one and three
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| (primary heart disease) and myocardial
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| | cardiovascular drugs because of CoQ10
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| infarction (irreversible injury to heart
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| | supplementation.These examples are just a
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| muscles). Heart muscle strength is
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| | drop in the bucket. Diastolic dysfunction
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| measure by the ejection fraction which is
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| | (and by proxy, hypertension) includes
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| a measure of the fraction of blood pumped
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| | only a small sampling of heart conditions
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| out of the heart with each beat. A low
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| | that respond favorably to CoQ10
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| ejection fraction indicates a weak
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| | supplementation. Other areas of research
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| heart.Several trials have been conducted
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| | show great promise for CoQ10 treatments.
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| involving patients with enlarged weak
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| | Among these are cancer and AIDS. But such
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| heart muscles of unknown causes. For
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| | conditions are beyond the scope of this
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| those of you who like difficult phrases
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| | essay. CoQ10 is essential to the proper
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| this condition (or variety of conditions)
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| | functioning of all cell types. It is not
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| is known as idiopathic dilated
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| | surprising, therefore, to find a diverse
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| cardiomyopathy. In these trials CoQ10
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| | number of diseases that respond favorably
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| supplementation was compared to placebo
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| | to CoQ10 supplementation. Since all
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| effects. Standard treatments for heart
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| | metabolically active tissues are highly
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| failure were not discontinued. The
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| | sensitive to CoQ10 deficiency, we can
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| results were measured by echocardiography
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| | expect to see CoQ10 research expand to
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| (a diagnostic test which uses ultrasound
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| | many other areas of chronic diseases.Greg
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| waves to make images of the heart
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| | holds degrees in science, divinity and
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| chambers, valves and surrounding
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| | philosophy and is currently an I.T.
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| structures).The overall results of CoQ10
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| | developer.
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| supplementation demonstrated a steady and
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