| The exact reason why colon cancer develops in | | | | cancer. On the other hand absence of all risk factors |
| some persons and not in others is not clear. The | | | | does not mean that an individual will not develop |
| incidence of colon cancer is quite varied among | | | | colorectal cancer, but generally more risk factors you |
| different countries and within different ethnic groups | | | | have higher is the chance of developing colorectal |
| inside the same country. Industrialized countries like | | | | cancer. Environmental factors also may be playing a |
| United States, Canada, UK, Western Europe, Australia | | | | role in the development of colorectal cancer. People |
| and Japan have a much higher incidence of colorectal | | | | who migrate from areas of low risk to areas of the |
| cancer compared to the less industrialized parts of | | | | world with higher risk of developing colorectal cancer, |
| the world like Asia, Africa, and South America. | | | | they tend to acquire the risk of the country to which |
| Colorectal cancer represent over 9 percent of all | | | | they are migrating. This finding suggests the |
| cancers in men and about 10 percent of all cancers in | | | | presence of environmental factors causing higher risk |
| women world-wide. In industrialized countries the | | | | of developing colorectal cancer. Changes in dietary |
| incidence of colorectal cancer can be as high as 12 to | | | | factors associated with migration may also be |
| 14 of all cancers, and in non-industrialized countries | | | | contributing to this increase in risk associated with |
| much lower rates of about 7 to 8 percent of all | | | | migration from low risk areas to higher risk areas. |
| cancers diagnosed may be colorectal cancer. | | | | Risk factors for the development of colorectal |
| Excluding skin cancer, colorectal cancer is the third | | | | cancer include the following: |
| commonest cancer diagnosed in the United States. | | | | - Age over 50 years |
| Each year over 100,000 Americans are diagnosed | | | | - Increased fat intake |
| with colon cancer and over 50 percent of these | | | | - Large intestinal polyps |
| patients will die from colorectal cancer. Colon cancer | | | | - Family history of colon cancer |
| incidence is not much different between males and | | | | - Inflammatory bowel diseases like ulcerative colitis |
| females, however colon cancer is slightly more | | | | and Crohn's disease. |
| prevalent in women compared to men (ratio of 1.2:1) | | | | - Personal history of other cancers |
| but the rectal cancer is more common in males (ratio | | | | - Sedentary habits and lack of exercise |
| of 1.7:1). | | | | - Obesity |
| Even though we do not know the exact cause of | | | | - Diabetes |
| development of colorectal cancer, scientists have | | | | - Smoking |
| recognized several factors that can increase the risk | | | | - Alcohol content |
| of development of colorectal cancer. A risk factor | | | | - Genetic colon cancer syndromes like Familial |
| for a disease is any condition that makes a person | | | | adenomatous polyposis or Hereditary Non-polyposis |
| more likely to develop that diseases. Some of the | | | | Colon Cancer (HNPCC) Persons who have high risk of |
| risk factors like dietary factors are modifiable by the | | | | colorectal cancer may undergo screening for |
| person involved while some other factors like age are | | | | colorectal cancer with colonoscopy once every 2 to |
| un-modifiable. These risk factors may act in | | | | 3 years. Screening colonoscopy is recommended for |
| combination, and this combination of risk factors may | | | | every one who is 50 years or older. If someone has |
| be associated with cumulative increase in the risk of | | | | a higher than average risk of developing colorectal |
| development of colorectal cancer. The simple | | | | cancer, the screening may be initiated earlier than 50 |
| presence of one or more risk factors does not | | | | years. |
| necessarily mean that someone will develop colorectal | | | | |