| A recent in the US is offering hope for
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| | why dogs are not trained to detect VOCs
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| testing for lung cancer. US scientists
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| | in the same manner that dogs are trained
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| have now developed and already tested a
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| | to detect drugs and other compounds.
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| prototype breath test to detect lung
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| | The prototype of this device was
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| cancer. This may enable doctors to detect
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| | developed by Dr Peter Mazzone of the The
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| lung cancer at earlier stages.
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| | Cleveland Clinic in Ohio in collaboration
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| The results of the US study test was
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| | with the private company ChemSensing of
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| published in the international journal of
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| | Champaign, Illinois. The private company
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| respiratory medicine Thorax.
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| | customizes Metalloporphyrins, a
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| In the tests, the colour testing device,
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| | chemically reactive dye family that are
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| which is the size of a coin and is
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| | sensitive to VOCs.
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| surprisingly inexpensive, had a 75 per
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| | They are working to develop an
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| cent success rate in detecting people
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| | inexpensive device. The only equipment
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| with different cancers.
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| | available to the public are mass
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| However, the tests were not 100 per cent
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| | spectrometers or gas chromatographs.
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| accurate. The device showed false
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| | These are expensive and require the
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| positives on people who did not have lung
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| | services of an expert to analyse the
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| cancer. This reduces the device's
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| | results.
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| effectiveness removing doctor's ability
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| | The new device resembles a 2 cm square
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| to start immediate treatments.
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| | key fob with a 6 by 6 pattern of coloured
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| The technique called a "colorimetric
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| | dots visible through the plastic casing.
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| sensor array" picks up the chemical
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| | Changes in the pattern of the dots
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| fingerprint of the breath of people with
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| | indicate the presence of VOCs in the
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| lung cancer that are caused by the
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| | breath based on the gas makeup of the
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| tumours.
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| | breath.
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| Cancers produce volatile organic
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| | Scientists tested 143 patients. Patients
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| compounds (VOCs) that are different from
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| | needed to breathe into the device for 12
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| normal cells. Tumours in the lungs are
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| | minutes. The test group was divided into
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| more likely to contain increased signs of
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| | three groups. Some patients had lung
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| these abnormal compounds. This increases
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| | cancer at various stages, some had other
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| the potential for the device to pick up a
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| | forms of respiratory illnesses like
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| lung cancer "fingerprint" in the breath.
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| | emphysema. The rest were healthy.
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| Surprisingly, dogs are able to detect
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| | The device spotted 73 per cent of the
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| VOCs and differentiate between people
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| | lung cancer patients and cleared 72 per
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| with lung cancer and healthy people. With
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| | cent of the non-lung cancer patients.
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| 'early response' a major factor in
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| | This is not 100 per cent, but the results
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| survival rates, there are many who wonder
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| | are acceptable.
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