| While treatment for prostate cancer
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| | injected directly into the prostate gland
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| varies, and men have a wide menu of
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| | to freeze and kill cancer cells. A study
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| choices, there are a few new treatment
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| | was done involving twenty men who had
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| options in the works that may soon be
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| | prostate cancer; all were given focal
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| available. A new vaccine, improved
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| | cryosurgery, and of the twenty, nineteen
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| cryosurgery, and a new gene-based therapy
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| | showed no signs of cancer as much as
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| are currently in development. The vaccine
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| | eight years later.
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| dubbed Provenge is currently on the FDA's
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| | The advantage of cryosurgery is that the
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| fast track program, cryosurgery has been
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| | procedure can be successfully performed
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| around for awhile but has seen some
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| | without resulting in the major side
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| recent advances in technique that make it
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| | effects of traditional prostate removal
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| more viable, and the new gene therapy
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| | surgery, such as impotence and
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| known as Ad5-TRAIL involves injecting a
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| | incontinence. Although not widely
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| virus carrying a prostate cancer fighting
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| | performed, focal cryosurgery is a
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| gene into the prostate gland itself. This
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| | promising new treatment that solves one
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| article will examine the current status
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| | of the major problems in men facing
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| and details of these new prostate cancer
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| | prostate cancer.
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| treatments.
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| | The third new treatment option is a
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| Dendreon Corporation's prostate cancer
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| | gene-based therapy called Ad5-TRAIL. The
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| vaccine known as Provenge is the most
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| | TRAIL gene is able to produce what's
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| promising new treatment of the three.
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| | known as apoptosis in cells, which is a
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| Intended for cancer that has spread
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| | "planned" cell death, as opposed to
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| outside the prostate gland and is so far
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| | necrosis, which is death due to injury.
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| without symptoms, the vaccine "teaches"
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| | The TRAIL gene is inserted into the
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| the patient's immune cells to attack the
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| | prostate gland via a virus that has been
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| cancer. Having just finished its second
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| | engineered to not reproduce, and passes
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| Phase 3 trial, the drug has shown a 30%
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| | the program for apoptosis on to the tumor
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| increase in survival rates among advanced
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| | cells, which then die.
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| prostate cancer patients. Since it fills
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| | The advantage to this therapy is that the
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| in a much-needed gap in the prostate
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| | programmed cell death only affects
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| cancer treatment field, it has been
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| | cancerous cells and leaves normal cells
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| granted "fast track" status with the
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| | alone. The treatment is still in its
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| United States' Federal Drug
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| | infancy and is currently only in Phase I
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| Administration, which will hopefully
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| | of its clinical trial.
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| speed along the approval process. While
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| | The future looks hopeful for prostate
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| Provenge may be useful for advanced
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| | cancer. New treatment options are in
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| prostate cancer, there is a new surgery
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| | their infancy, but a few are on the verge
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| for cancer patients in whom the disease
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| | of becoming reality. Provenge is on track
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| is confined to the prostate gland.
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| | to FDA approval, and focal cryosurgery is
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| Also known as the "male lumpectomy,"
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| | available today. While Ad5-TRAIL gene
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| cryosurgery has been around for some
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| | therapy is years away from becoming a
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| decades. However, some recent advances in
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| | viable treatment, it perhaps looks the
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| it have increased its potential
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| | most promising as a targeted, gene-based
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| effectiveness. The latest incarnation,
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| | therapy that directly attacks only cancer
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| focal cryosurgery, uses argon gas
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| | cells.
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