Liver Cancer - Related to Hepatitis B Carrier State?

Liver cancer refers to either primary liver cancer, thatmothers were discovered to be carriers of hepatitis
is cancer originating from the liver cells or supportingB. This compares significantly to the incidence of 1%
cells in the liver, or secondary liver cancer, that isin the United States. Similar studies show a higher
cancer that has spread to the liver from theincidence of hepatitis B carrier rates in South-East
surrounding organs, usually via the blood that drainsAsian countries, between 10% to 15%. This has led
those organs and flow through the liver. In this articleto the belief that Oriental persons are genetically less
we shall confine ourselves to primary liver cancer,able to overcome the hepatitis B virus. This
also referred to as hepatocellular carcinoma.observation is supported by another observation,
Liver cancer is one of the more commonly occurringthat the conversion rate to immunization with
cancers in the world, being the fifth most commonhepatitis B vaccine is lower in Chinese as compared
cancer in men and the eighth most common cancer inwith other races.
women. The total number of new cases diagnosed isStudies also show that the incidence of new cases
estimated to be about 500,000 every year. Menof primary liver cancer has decreased significantly in
seem to be twice as likely as women to get liverthose countries where there has been a deliberate
cancer.effort to immunize persons to hepatitis B with
What could cause this problem?hepatitis B vaccine. This is one of the rare situations
The incidence of liver cancer seems to be higher inwhere there is a demonstrable cause/effect
certain countries. Studies appear to indicate a positiverelationship, and where there is definite proof that a
relationship between the incidence of liver cancer andparticular cancer can be prevented, by both
that of hepatitis B virus carrier states as well asvaccination and by screening of blood and blood
hepatitis C virus infections. The risk of a hepatitis Bproducts for hepatitis B and C viruses.
carrier developing liver cancer is about 60 timesOther risk factors or suspected causes of liver
higher than that of a non hepatitis B carrier. This riskcancer need to be mentioned here. They are:
appears to be even higher than the risk of a smokerLiver Cirrhosis. A situation of scarring of the liver due
developing lung cancer (about 20 to 25 times).to chronic damage as a result commonly of heavy
What countries have a higher incidence of hepatitis Bdrinking. There is a slight increase of risk of liver
carrier states? It is observed that certain countriescancer developing.
seem to have a much higher incidence of hepatitis BInherited causes. Persons with hemochromatosis, a
carriers. One case in point is Taiwan, where it isgenetic problem of excess iron deposits in the body
noted that an abnormally high 20% of pregnanthave a higher chance of developing liver cancer.