Is Gene Testing for Breast Cancer Reliable?

For a woman, being diagnosed with breast cancer isQuestions are being asked whether the test is a
one of the most traumatic experiences in life. Oncereliable indicator. Perhaps it could be that only the
the disease is detected the uphill climb of physicalparticular tests that showed negative, when in fact
exhaustion due to medical treatment and thethe patient had breast cancer, were in error.
emotional trauma of going through the side effectsSome women may carry mutations of the BRCA1
of treatment begins.and BRCA2 genes which may result in a false
The earlier breast cancer is detected the better thenegative test result. These mutations may not be
chances are for complete cure. Therefore, there isdetected by the normal gene testing methods.
constant emphasis on getting routine mammogramsThe test that is available today for detecting breast
and other screening for breast cancer for all women,cancer genes BRCA1 and BRCA2, is patented by
especially those above the age of 40 and those whoMyriad Genetics. The test is known to miss several
have a history of breast cancer in the family.alterations or mutations in the genes. Almost twelve
Breast and ovarian cancer are thought to havepercent of the population with a family history of
strong genetic links. There are also several tests tobreast cancer may test normal or false negative. If
detect the genes that are linked to both types ofthe test comes back normal, but you suspect a high
cancer. But now these tests have been reported toprobability of genetic link what is the ideal course of
miss many cases, some of which even on womenaction?
who have a family history of breast cancer and haveHealthcare professionals advise that if a strong
developed the disease earlier.genetic link is suspected, women are to act as
If new research is any indication, Breast Cancer genethough the test is positive even if they tested
testing is not as reliable as it was initially thought tonormal. Regularly follow up with CAT scans and
be. The genes that are linked to breast cancer areMRI’s, and it may be possible to detect breast
the BRCA1 and BRCA2 genes – Breast Cancer 1cancer in the initial stages. “Better safe than
and Breast Cancer 2 genes. The tests for thesesorry” seems to be the guiding principle that
abnormal genes proved to be negative in some casesmust be adopted in the ongoing battle against breast
where the patient was diagnosed with breast cancer.cancer.