How Effective Is Chemotherapy For Breast Cancer?

After mastectomy, women are sent to see theAustralian doctors: Graeme Morgan, Robyn Ward
oncologists, and they are often told to go for& Michael Baton noted that in Australia, of the
chemotherapy. This treatment is like an "insurance"10,661 people who had breast cancer only 164 people
against future problems. Chemotherapy can kill all thesurvived five years due to chemotherapy. This
remaining cancer cells in the body. In this way theworks out to 1.5% contribution of chemotherapy to
cancer can be cured. Chemotherapy can also stopsurvival. In their paper, they concluded that "overall
cancer from spreading to other parts of the body. Orcontribution of curative and adjuvant chemotherapy
at the very least it slows the cancer growth. To theto five-year survival in adults was estimated to be
oncologists, chemotherapy is the proven way to go,2.3% in Australia and 2.1% in the USA."
other ways are hocus pocus!Professor Michael Boyer, head of Medical Oncology of
These points are often well taken by women inthe Sydney Cancer Centre, Royal Prince Alfred
general. The fear of recurrence is sufficient enoughHospital disputed this 2% figure. He said: "It's not
to make women go through chemotherapy. Tocorrect for a number of reasons. The 2% figure is
them, the sufferings of the treatment are worthachieved by including a whole series of diseases in
enduring for the promise of cure at the end of thewhich chemotherapy would never be used." To the
adventure. What some oncologists don't tell theirprofessor the more "correct" figures should be 5%
patients is that not all the cancer cells are killed byor 6%. Okay, let us accept that new figures -- how
the treatment. There is no way that a hundreddo women feel about it -- going for chemotherapy to
percent of the cancer cells can be wiped byachieve a five to six percent success?
chemotherapy. Add to that, even the good healthyIn the editorial of the Australian Prescriber (2006.
cells are killed and the immune system destroyed.29:2-3), Eva Segelov wrote: "Chemotherapy has been
Patients, on the other hand don't ask theseoversold. Chemotherapy has improved survival by
questions: Will there truly be a cure? If indeed theless than 3% in adults with cancer."
promise of cure is real, can we put it in terms of realVeroort et al. from the Netherlands (British J. Cancer.
numbers or percentage? To put it bluntly, how2004. 91: 242-247) in their study on the role of
effective is chemotherapy for breast cancer? Itamoxifen and chemotherapy for breast cancer
wonder how many women ask their oncologistsconcluded that "breast cancer mortality reduction
these questions, and if they do, what would thecaused by present-day practice of adjuvant
answers be like?a) Without chemotherapy whattamoxifen and chemotherapy is 7%. Tamoxifen
percentage of people died or would die from breastcontributes most to the mortality reduction. The
cancer?b) With chemotherapy what percentage ofoverall effect of chemotherapy on mortality is very
people are cured or would be cured?c) What issmall." Take note that the contribution of
meant by cure?chemotherapy to breast cancer survival is very small
Try and search the answers from the internet and- what is very small? To be sure it has to be much,
see if you can get anything. There is a great chancemuch less than 7%.
that you will go on a merry go round trip! IGuy Faguet, after spending numerous years of
experienced exactly just that and was terriblyresearch on cancer, came to this startling conclusion
disappointed. Thousands of articles are written about(The War on Cancer: An anatomy of failure, a
breast cancer but I fail to find the clear-cut answersblueprint for the future. Springer, 2005): "An objective
to the above questions. Perhaps they are notanalysis of cancer chemotherapy outcomes over the
important? Or something that women do not needlast three decades reveals that, despite vast human
to know before they embark on their treatment?and financial expenditures, the cell-killing paradigm had
Women just need to have full faith and trust in thefailed to achieve its objective ... the conquest of
experts and everything would turn out fine. Fewcancer remains a distant and elusive goal."
women realize that such attitude may just be theChemotherapy for cancer is based on "flawed
beginning of more problems to come.premises with an unattainable goal, cytotoxic
Let me try to share what I have gathered from thechemotherapy in its present form will neither
medical literature.eradicate cancer not alleviate suffering."
Karin Stabiner in her book (To dance with the devil)Cured of Breast Cancer?
wrote: "Breast cancer takes the life of an AmericanIn a study of 1,547 breast cancer patients at the
woman every twelve minutes. There is no sure cureUniversity of Chicago Hospital, USA, from 1945 to
for the disease, no known way to prevent it and no1987, Theodore Karrison et al. (J. Nat. Cancer Inst.
means of predicting." With all the advances in science1999. 91:80-85) observed that for patients who
and technology, may I ask, how could this be? Whyunderwent mastectomy but without chemotherapy
such high degree of uncertainty?or radiotherapy, most recurrences occurred within
Chantal Bernard-Marty, Fatima Cardoso, Martine J.the first ten years after mastectomy. Recurrences
Piccart of Jules Bordet Institute, Brussels, Belgiumwere rare after 20 to 25 years. Patients surviving to
(The Oncologist 9: 617-632, Nov. 2004) wrote:this time without evidence of recurrence are
"20%-85% of patients ... who are diagnosed withprobably cured.
early breast cancer will later develop recurrent and/orWomen are often told that if they survive five years
metastatic disease. Despite more than 3 decades ofafter their diagnosis of breast cancer, they are
research, metastatic breast cancer remains essentiallyconsidered cured of breast cancer. Based on the
incurable." Women are told that "catching" breastwork of Karrison et al. this assumption is
cancer early is a sure way of saving life. But how is itpresumptuous and is not true at all. Women perhaps
that even after early detection, twenty toneed to be reminded of what Guy Faguet wrote:
eighty-five percent of patients still go on to develop"We must recognize that "cure" is not an absolute
more serious cancer that is incurable? Has theterm because minimal residual or slowly recurrent
treatment protocols got anything to do with suchdisease that causes no symptoms can persist and
failures?remain undetected for years." Take note, the cancer
How effective is chemotherapy?can remain dormant in the body for years not just
Writing in Clinical Oncology (2004. 16: 549-560), threefive years!