Estrogen and Breast Cancer - The Evolving Mystery

As many women begin the transition throughBy how much the risk is increased is not exactly clear
menopause a lot of consideration goes into the ideaat this point and will likely vary depending on each
of taking Hormone Replacements - whether it is justwoman's unique genetic makeup, diet and exposure
Estrogen (Estrogen Therapy or ET) or a combinationto various environmental factors. Obviously, the risk
of Estrogen and Progesterone (Hormone Therapy orfactor of taking HRT has a much greater impact if
HT). For the purpose of this article Hormoneyou are already at risk of developing breast cancer.
Replacement Therapy (HRT) will refer to both HTIf you fit into any of the categories below - then
and ET.most physicians would probably agree that you
Replacing your hormones with either natural orshould avoid HRT.
synthetic (laboratory made) forms of hormones may- If you are a breast cancer survivor: The concern is
offer some benefit by helping to reduce many of thethat HRT may stimulate the growth of small or
symptoms of early menopause - such as, hot flashes,hidden tumors, it is nearly impossible to determine
insomnia, moodiness, and vaginal dryness. As well ashow many women harbor these hidden cells known
more serious problems that may result fromas micrometastases.
menopause like weakened bones, and osteoporosis.- If you have a family history of breast cancer: It is
But as with EVERY pharmaceutical product made tonot clear whether women with a family history are
help relieve pain or discomfort there are risks, andat increased risk of developing breast cancer when
hormone therapy is not without them. What'staking HRT and therefore the medical community is
important is that your unique health history and riskcautious about recommending it.
factors are discussed with your doctor to best- If you have a history of: Uterine cancer, Liver
determine whether or not HT or ET is the bestdisease, Blood clots, Undiagnosed vaginal bleeding or
option for you.Heart disease.
Estrogens Impact on the BreastOne major consideration when contemplating HRT
What you have to recognize is that the scientificshould be whether or not you are at a higher than
community is just beginning to realize the uniquenessaverage risk of developing breast cancer. Some other
of every woman's hormone profile. The effect ofminor factors that may increase your cancer risk are
HRT on one of your female friends may be vastlyweight gain and women who experience menopause
different from the effect they have on you. This islater in life than average.
why there is such a large amount of variation in whatHRT - A Personal Decision
each woman experiences as they transition throughHRT is really a personal choice - there is no right or
menopause. This is also one of the greatestwrong answer. While some women may not want to
challenges that Doctor's and Scientist face in theiraccept the risks associated with HRT others may
effort to understand the affects HRT has on thewant to. Each woman must decide for herself, with
female breast.input from her doctor, the best course of action.
Probably the biggest concern women have aboutBoth patient and doctor should be comfortable with
HRT is the increased risk of that dreaded disease -the decision to take HRT or to pursue other
Breast Cancer! Breast cancer risk, like many diseases,treatments.
increases with age for women, but it is notIf you do decide to try HRT make sure you work
specifically affected by menopause. Unfortunately,closely with your doctor - prescribing the right
recent studies have generated a lot of conflictingdosage may sometimes turn into a bit of a guessing
data between HRT and breast cancer risk.game. Keep your doctor informed as to how you are
But, before I go into the risk of developing breastfeeling and whether or not you think it is helping. The
cancers from HRT, it is important that youbest thing you can do is actually keep a journal and
understand how Estrogen and Progesteronetrack the symptoms that you're hoping HRT will help
hormones affect your body, or more particularly,with. The lower the dosages and the shorter the
your breasts.duration is best if you are worried about increased
There are two primary thoughts on how cancerbreast cancer risk. But again your personal situation
develops in the breast. One is that cancer tends toshould be discussed in detail with your doctor, if you
appear in fast growing tissue - Estrogen (andhave another medical condition where the benefits
Progesterone) can cause breast tissue to grow at aHRT provide outweigh the increased breast cancer
faster rate - therefore this may be one wayrisk, then HRT should be considered.
Estrogen is related to developing breast cancer. AIf HRT is not for you - you are not without help.
second theory is that when estrogen is broken downThanks to all the ongoing research, new therapies
in breast tissue the resultant compounds may bind toand alternatives are being investigated every day and
genetic material (DNA) and damage it. Damaged DNAhave proven successful for many women. But a
is a common cause of cancers. For the moment -word of warning - since this is a very new field, don't
these are two primary theories on how HRT maynecessarily believe every thing you hear and read.
increase the development of breast cancer.There are a lot of companies trying to take
Understand that the scientific community is hard atadvantage of this relatively new market. And since a
work trying to unravel the link between Estrogen andlot of the herbal remedies are not regulated by the
Breast Cancer -- or if there is even really a link -- butFDA some companies will package almost anything
good science takes time. There are so manywith no regard for scientific data to back up their
variables (like medical history and diet) in every studyclaims. Look for resources that are impartial and
that it is impossible to blame ET or HT alone forcompanies that provide actual data to support what
breast cancer. Although the results of many clinicalthey are claiming.
trials does show that HRT MAY increase the risk ofLastly, I personally am an advocate of a healthy diet
developing breast cancer.and active lifestyle to beat menopausal symptoms
The Risk Factorsand weight gain -- you should know that every clinical
As a result of the various studies and clinical trialsstudy I have read has shown that these two factors
done, one thing is for sure, many more studies willare proven to ease the menopause transition by
need to be done before we unravel the mystery ofregulating hormones naturally. And with no increased
HRT and breast cancer. In the mean time be awarerisk of breast cancer -- actually eating the right foods
of the fact that:will help prevent breast cancer as well as many other
Breast cancer risk is increased with the use of ET,types of cancer and disease. So regardless of your
and to a greater extent with HT, use beyond 5HRT decision -- the first step you should take when
years. And observational data suggest a slightit comes to helping yourself is to eat a proper
potential increase for breast cancer with HRT use formacronutrient profile and get that body of yours
less than five years.moving!