Diabetes, Breast Cancer and Metabolism - The Current Position

As the level of obesity has risen exponentially in thewomen. This link is strong enough to suggest that
Western World so has the incidence of insulindiabetes can lead to breast cancer.
resistance and type two diabetes. There appears toIn the study by Weiderpass et al in 1997 diabetes
be a link between obesity and post menopausalwas assessed at baseline, and the subsequent
women and breast cancer, but that link is hard torelative risk for breast cancer diagnosed after five to
prove as the risk factors for both are similar, anine years, but it found that the risk was no higher
sedentary lifestyle, a high intake of refinedthan in the one to four year periods. Michels et al
carbohydrates such as white sugar, white bread and2003 found an increase in the incidence of cancer
white pasta and a high level of fats and obesity.after fifteen years in diabetic patients. However the
The metabolic link between diabetes and obesity isstudy was only small because of the gap of fifteen
there but the role of breast cancer and metabolismyears. Some doctors believe that insulin concentration
has only recently studies in September 2007.drop in the later stages of type 2 diabetes ad this
Statistically, the increase in this kind of cancer hasmay cause the increased risk to shrink over time and
been steady since the 1930s until the present day,not get worse. A statistically significant positive
except data from the National Cancer Institute'sassociation between diabetes mellitus and the risk of
Surveillance Epidemiology and End Results (SEER), thecancer remained in only three case studies over
incidence of breast cancer dropped from 2001 totwenty years.
2003 by 4.8% annually.Although the overall mortality rate for breast cancer
It was presumed that this fall was a result of anhas decreased in the past 15 years because of earlier
increased awareness of the need for women todiagnosis and better drugs, diabetes has been linked
have mammograms and also a correspondingto increased mortality from breast cancer. Coughlin et
reduction in the amount of women undergoing HRT.al followed 1.2 million US men and women twice a
In 1980, 5.8 million Americans were diabetic ( middleyear from 1982 to 1988 and found that women with
aged diabetics) while that figure has soared to nearlydiabetes were more likely to die from breast cancer
fifteen million by 2005.than were women not diagnosed with diabetes.
Since the 1950s, women with breast cancer have hadSimilar studies in Italy have supported the claim that
higher rates of diabetes than do healthy women inthere is a direct causal relationship between diabetes
the same age group. Seven studies have found aand cancer and that diabetes also accelerated the
strong association between cancer and diabetes ingrowth of tumors and made it less likely that women
women after the menopause yet there has been nowould get to a five year survival rate.
strong evidence that there is a link in pre menopausal