| Its targeted action on cancerous white blood cells | | | | hypereosinophilic Syndrome, another blood cancer |
| produced by the abnormally functioning bone marrow | | | | with an abnormally high multiplication rate of the |
| also showed less side-effects comparing to prior used | | | | eosinophilic blood cells responsible for fighting against |
| drugs. Bone Cancer Treatment CostGleevec has a | | | | parasite-linked diseases and allergies. |
| small rate of toxicity causing nausea, skin rashes or | | | | Lung Cancer Secrets Revealed Click here |
| fluid retention but is far more advantageous than | | | | Eosinohils are a type of white blood cells representing |
| drugs injuring internal organs like heart, kidneys or | | | | about 3-5% of the total number of leucocytes in the |
| lungs or attacking normal tissues while killing cancer | | | | human blood. The hypereosinophilic syndrome |
| cells. | | | | develops with an accumulation of outnumbered |
| Since 2001 Gleevec has been successfully used in | | | | eosinophils inside the bloodstream. They have major |
| curing other cancer types as well, due to its targeted | | | | toxic properties in large numbers and have toxic |
| action on the abnormal tyrosine kinases sending | | | | effects on tissues such as heart and nervous |
| wrong signals to active cells. At least three other | | | | system. This disease is known to have multiple |
| cancerous conditions are known to be caused by | | | | causes and therefore many possible pathological |
| genetically modified tyrosine kinases. The | | | | types. The study with Gleevec administration was |
| gastrointestinal stromal tumor was earlier a very | | | | made on the chronic hypereosinophilic Leukemia and |
| difficult to treat disease; it is caused by a different | | | | the patients’ condition was substantially |
| type of tyrosine kinases than the one responsible for | | | | improved. |
| chronic myeloid Leukemia but Gleevec could | | | | The detection of Gleevec was a real scientific |
| successfully inhibit it as well. | | | | success as it was able to treat conditions with no |
| About 60% of the patients with this tumor treated | | | | other possible therapies. In case of the chronic |
| with Gleevec showed remarkable improvement and | | | | myeloid Leukemia the bone transplant is the most |
| real benefic effects but doctors must still wait a few | | | | efficient cure but is has many side-effects and can |
| years to know how long the effects will last. | | | | only be performed on some patient types. Gleevec |
| The chronic myelomonocytic leukemia is another very | | | | was a second chance for the patients with real |
| rare encountered blood disease upon which Gleevec | | | | benefits as it can be self-administered due to its pill |
| proved to be efficient. Myelomonocytic Leukemia is a | | | | form. |
| particular type of myeloid Leukemia also caused by a | | | | Gleevec is not yet the magic cure in cancer as it can |
| genetically modified tyrosine kinases. The third | | | | produce no molecular changes on genetic mistakes |
| cancerous condition with great improvements after | | | | but its discovery has shown that we are close to |
| the chemotherapy with Gleevec is the | | | | finding a real therapy for cancer. |