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Article #164: About Antibodies for Cancer Prevention

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The latest discoveries in medical Mabs is available through the ACA's web
technology are using certain antibodies site. In 2004 and in 2006, Bevacizumab, a
for cancer prevention. These medical naked antibody, was approved for treating
miracles are called monoclonal certain types of breast cancers.
antibodies, or "Mabs", and can be used to In 2001 the FDA approved the use of
help ward off all kinds of cancers. The Alemuzumab, a naked antibody, which acts
technology to aid doctors and nurses as a form of leukemia prevention by
fight cancer has only come about within attaching itself to both B and T cancer
the last several decades. Further cells, causing the body's immune system
research continually turns up more and to attack and kill them. In 2000, the FDA
more Mabs, providing hope for those who approved the use of a conjugated
have already developed cancer and for antibody, Gemtuzumab ozogamicin, which is
those who are trying to protect used in the treatment of chronic
themselves from it. leukemia.
The American Cancer Society's (AMC) web If you have lost someone to cancer or
site explains that monoclonal antibodies know someone suffering from cancer, it is
were first developed in laboratories not hard to understand how crucial
using mice with myeloma cells, which is a medical research is when it comes to
kind of bone marrow cancer, and mice that finding antibodies for cancer prevention.
produced specific antibodies for those The number of cancer victims continues to
cells. The combination of these two rise each year, hitting people of all
cells, called a hybridoma cell, forces a ages.
perpetual factory making antibodies. With the prolonged use and approval of
The antibodies end up being identical Mabs, these numbers may begin to decline,
clones of the original hybridoma cell, alleviating the fear everyone has about
which is why they are called monoclonal developing some form of the deadly
antibodies. The problem scientists faced disease. Diet and exercise will only help
with this phenomenal finding was that an individual a certain amount, leaving
human antibodies recognized the genetics and medical breakthroughs to do
mouse-produced antibodies as foreign the rest.
invaders and attacked them. By continuing to fine tune more
With hard work and dedication, scientists variations of antibodies for cancer
are continuing to develop ways to prevention, medicine as we know it today
integrate human antibodies in lieu of could be changed for the better in years
mouse antibodies so cancer patients will to come.
be able to use the immunotherapy as a Medicine has come a long way in the last
form of treatment. fifty years thanks to the help of
Today there are two types of Mabs, naked scientists and research laboratories.
and conjugated. The difference between Their combined efforts have aided
these two lies in the fact that naked individuals all over the world prevent
antibodies lack radioactive materials and treat life-threatening forms of
attached to them. Conjugated antibodies, cancer.
on the other hand, are fused with a Advancements in immunotherapy treatments
chemotherapy drug or other toxin used to that use antibodies for cancer
fight off cancer cells. prevention, combined with other
In recent years the Food and Drug cancer-deterring methods, are just a step
Administration (FDA) has approved several on the threshold for greater triumphs to
Mabs, both naked and conjugated, for help everyone live long and healthy
cancer treatments. A list of approved lives.






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